Resolve^A19 RAIN ROT – RAIN SCALD
Rain Rot is caused by the gram-positive facultative anaerobic actinomycete Dermatophilus congolensis.  Lesions develop because of damage to the skin in the presence of moisture, which induces the release of infective, motile, flagellated zoospores that are attracted to low concentrations of CO².  As organisms multiply, inflammatory cells migrate into the area increasing CO² concentrations.  The organisms then multiply, inflammatory cells migrate toward the skin (and lower CO²), and this process repeats itself over and over, resulting in signs of layered crusting and matting of the coat. 

Medicated shampoos containing iodine or chlorhexidine can be effective in mild cases but have undesirable side effects of irritation to the mucous membranes, eyes, and respiratory tissues.  Repeated use can also cause an excessive drying and cracking of the skin.  They have limited residual effects because they are rinsed off after application. Resolve^A19 Rain Rot was formulated with six lethal antimicrobial compounds and humectants that specifically target gram-positive organisms: aerobic, anaerobic; and faculatively anaerobic organisms.  Its chemistry has the ability to hasten recovery time, reduce severity and prevent transmission to other animals and humans.  It also continues to work in the presence of moisture.

 

Other gram-positive dermatological conditions that respond to this antimicrobial spray include:

• Grease-heel
• Scratches
• Dew-poisoning
• Bacterial Folliculitis/Bacterial Furnculosis caused by Staphylococcal or Streptococcal  
  species and rarely fungi
• Necrotizing Fasciitis (primarily due to a group A Streptococcus)
• Pastern Follicultitis caused Staphylococcus aureus, S. hycus, and possibly S. intermedius
• Dermatophilosis in the pastern region “Mud Rash” caused by Dermatophilus congolensis  
  but often seen with Staphylococcal or Streptococcal opportunistic infections
• Staphylococcal Dermititus “Saddle Rash”
• Streptococcal Dermititus/Folliculitis caused by Streptococcus equi equi “Strangles” or sometimes referred to as Streptococcus equi zooepidermicus.

Resolve^A19 RINGWORM
Dermotophytosis is the most contagious skin disease in horses.  Trichophyton equinum, Trichophyton mentagrophytes, microsporum gypsum, and microsporum canis are the most frequent isolates. 

Considering ARDA was created 18 years ago to look at trichophyton, and considering that ARDA-19 was awarded a federal contract over the “rest of the best," it stands to reason that we know how to eliminate it chemically.

An evaluation of the fungicidal efficacy of our formulation (at 1:32,000) suggests it is the fungicide of choice, certainly while maintaining safety for the horse, user, and the environment.  As with all our Resolve^A19 products, this formulation continues to work in wet conditions.

Resolve^A19 THRUSH
Thrush is caused by a bacterial infection in the central and collateral sulci of the frog.  Gram negative rods are isolated in all cases.  Fuscobacterium necrophorum is universally implicated as the causative anaerobic bacteria responsible for the black degenerative exudative dermatitis.  It is documented that anaerobic bacteria are aided by aerobic and/or faculatively anaerobic organisms which preferentially metabolize oxygen, creating an even more suitable environment for the growth of anaerobic bacteria.  Resolve^A19 Thrush was specifically formulated to target these aerobic and anaerobic bacteria.  At biocidal concentrations (typically 5ppm), the electrical charge of the cell membrane is disrupted, causing leakage of low molecular weight cell components, thereby killing the cell.  Most importantly, the chemistry was designed to work in continuously wet conditions.

For further information, please contact Equine Safety Zone, LLC. 
 (866)-383-8319